Chronic hemolytic anemia due to a monoclonal IgG cold agglutinin with anti-Pr specificity.

نویسندگان

  • K Dellagi
  • J C Brouet
  • C Schenmetzler
  • V Praloran
چکیده

Immunologic studies performed in a case of autoimmune chronic hemolytic anemia with low titer cold agglutinins (1/16) demonstrated that the cold agglutinins corresponded to monoclonal IgG with anti-Pr specificity. This antibody had a large thermal amplitude, being active at 37 degrees C. These unusual characteristics may define a distinct subset of chronic cold agglutinin disease.

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عنوان ژورنال:
  • Blood

دوره 57 1  شماره 

صفحات  -

تاریخ انتشار 1981